John Boscardin, PhD

Associate Professor of Medicine and Biostatistics

Contact Information

Office Address:
San Francisco VA Medical Center
4150 Clement Street (181G)
San Francisco, CA 94121

Phone: 415-221-4810 x3621
Fax: 415-750-6641
Email: john.boscardin@ucsf.edu

Click here to download Curriculum Vitae (pdf)

Areas of Specialization/Research Interests

Bayesian statistics

Longitudinal data modeling

Dependence structures for mixed data types

Missing data problems

Clinical trial design

State space models

Meta-analysis

Selected Publications/Presentations

Methodological

Boscardin WJ, Taylor JMG, & Law N. Longitudinal models for AIDS marker data. Stat Methods Med Res 7:13-27, 1998.

Boscardin WJ and Zhang X (2004). Modeling the covariance and correlation matrix of repeated measures.  Applied Bayesian Modeling and Causal Inference from Incomplete-Data Perspectives, Gelman and Meng, editors, New York , Wiley.

Yang X, Belin TR, & Boscardin WJ. Imputation and variable selection in linear regression models with missing covariates. Biometrics 68:498-506, 2005.

Zhang X, Boscardin WJ, & Belin, TR.  Sampling correlation matrices in Bayesian models with correlated latent variables. J Comput Graph Stat 15:880-896, 2006.

Boscardin WJ, Yan X, Wong WK.  A reanalysis of a longitudinal Scleroderma clinical trial using informative dropout models.  J Stat Plan Infer 137:3848-58, 2007.

Gelman A, Zaiying H, van Dyk DA, and Boscardin WJ. Using redundant parameterizations to fit hierarchical models. J Comput Graph Stat, 17:95-122, 2008.

Zhang X, Boscardin WJ, and Belin TR. Multivariate extensions to multinomial probit models using parameter-extended Metropolis-Hastings. Comput Stat Data An, 52:3697-3708, 2008.

Boscardin WJ, Zhang X, and Belin TR. Modeling a mixture of ordinal and continuous repeated measures. J Stat Comput Sim, 2008 (in press).

Health Services Research / Geriatrics / Cardiology

Fahey JL, Schnelle JF, Boscardin WJ, Thomas JK, Gorre ME, Aziz N, Sadeghi H, & Nishanian P. Distinct categories of immunologic changes in frail elderly. Mech Ageing Dev 15:1-20, 2000.

Wong MD, Shapiro MF, Boscardin WJ, & Ettner SL.  Contribution of major diseases to disparities in mortality. New Engl J Med 347:1585-92, 2002.

Chung JH, Boscardin WJ, Garite TJ, Lagrew DC, & Porto M. Ethnic differences in birth weight by gestational age: at least a partial explanation for the Hispanic epidemiologic paradox? Am J Obstet Gynecol 189:1058-62, 2003.

Fonarow GC, Adams KF, Abraham WT, Yancy CW, & Boscardin WJ. Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis of the ADHERE® registry. J Amer Med Assoc 293:572-80, 2005.

Wong MD, Chung A, Li M, Hsieh H, Shapiro MF, Ettner SL, & Boscardin WJ. The contribution of specific causes to sex differences in mortality.  Public Health Rep 121:746-754, 2006.

Wong MD, Tagawa T, Hsieh H, Shapiro MF, Boscardin WJ, & Ettner SL. Disparities in cause-specific mortality between Latino and white adults. Med Care 43:1058-62, 2005.

FitzGerald JD, Boscardin WJ, Hahn BH, & Ettner SL.  Impact of the Medicare short stay transfer policy on patients undergoing major orthopedic surgery.  Health Serv Res 42:25-44, 2006.

Mojica CM, Bastani R, Boscardin WJ, and Ponce NA. Low income women with breast abnormalities: system predictors of timely diagnostic resolution.  Cancer Control 14:176-82, 2007.

Mojica CM, Bastani R, Ponce NA, and Boscardin WJ. Latinas with abnormal breast findings: patient predictors of timely diagnostic resolution. J Womens Health, 16:1468-77, 2007.

HIV/AIDS

Goetz MB, Boscardin WJ, Wiley D, & Alkasspooles S. Decreased Recovery of CD4+ Lymphocytes in Older HIV-Infected Patients Beginning HAART. AIDS 15:1576-9, 2001.

Yang OO, Boscardin WJ, Matud J, Hausner MA, Hultin LE, Hultin PM, Shih R, Ferbas J, Siegal FP, Shodell M, Shearer GM, Grene E, Carrington M, O'Brien S, Price CB, Detels R, Jamieson BD, & Giorgi JV. Imm. profile of highly exposed yet HIV type 1-seronegative men. AIDS Res Hum Retrov 18:1051-65, 2002.

Widney D, Boscardin WJ, Kasravi A, & Martínez-Maza O. Expression and function of CD28 on Epstein-Barr virus- (EBV) positive B cell lines and AIDS-associated non-Hodgkin's lymphoma cell lines. Tumor Biol  24:82-93, 2003.

Breen EC, Boscardin WJ, Detels R, Jacobson LP, Smith MW, O’Brien SJ, Chmiel JS, Rinaldo CR, Laia S, & Martínez-Maza O. Non-Hodgkin's B cell lymphoma in persons with AIDS is preceded by increased serum levels of IL10, and is associated with a high IL10-expressing genotype. Clin Immunol 109:119-29, 2003.

McGowan I, Elliott J, Fuerst M, Taing P, Boscardin WJ, & Anton P. Increased HIV-1 mucosal replication is associated with generalized mucosal cytokine activation. JAIDS 37:1228-36, 2004.

Poles MA, Boscardin WJ, Elliott J, Taing P, Fuerst M, McGowan I, Brown S, & Anton PA.  Lack of decay of HIV-1 in latent GALT reservoirs in maximally suppressed individuals.  JAIDS 43:65-68, 2006.

McGowan I, Elliott J, Cortina G, Andrews K, Siboliban C, Adler A, Cho D, Boscardin WJ, Soto-Torres L, Anton PA. Characterization of Baseline Intestinal Mucosal Indices of Injury and Inflammation in Men for Use in Rectal Microbicide Trials (HPTN-056). JAIDS, 46:417-25, 2007.

Epeldeui M, Breen EC, Hung YP, Boscardin WJ, Detels R, Martinez-Maza O. Elevated expression of activation induced cytidine deaminase (AID) in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis. AIDS, 21:2265-70, 2007.


Traumatic Brain Injury / Brain Imaging

Vespa PM, Boscardin WJ, Hovda DA, McArthur DL, Nuwer MR, Martin NA, Nenov V, Glenn TC, Bergsneider M, Kelly DF, & Becker DP. Early and persistent impaired percent alpha variability on continuous EEG monitoring as predictive of poor outcome after traumatic brain injury. J Neurosurg 97:84-92, 2002.

Glenn TC, Kelly DF, Boscardin WJ, McArthur DL, Vespa P, Oertel M, Hovda DA, Bergsneider M, Hillered L, & Martin NA. Energy dysfunction as a predictor of outcome after moderate or severe head injury: indices of oxygen, glucose and lactate metabolism. J Cerebr Blood F Met  23:1239-50, 2003.

Dinov I, Boscardin WJ, Mega MS, Sowell EL, & Toga AW. A wavelet-based statistical analysis of fMRI data: I. Motivation and data distribution modeling. Neuroinformatics 3:319-42, 2005.

Oertel M, Boscardin WJ, Obrist WD, Glenn TC, McArthur DL, Gravori T, Lee JH, & Martin NA.  Posttraumatic vasospasm: epidemiology, severity and time course of an underestimated phenomenon – a prospective study in 299 patients. J Neurosurg 103:812-24, 2005.

Gonzalez NR, Glenn TC, Boscardin WJ, Vespa PA, Vinuela F, and Martin NA.  Vasospasm probability index: a combination of TCD velocities, cerebral blood flow, and clinical risk factors to predict cerebral vasospasm after aneurysm subarachnoid hemorrhage. J Neurosurg, 107:1101-12, 2007.